Diabetes and life-long cognitive ability

Explorer Diabetes and life - long cognitive ability

Childhood Cognitive Ability Moderates Later-Life Manifestation of Type 2 Diabetes Genetic Risk

OBJECTIVE The study investigated whether childhood cognitive ability moderates Type 2 diabetes polygenic risk manifestation in older age. METHOD In 940 relatively healthy people (mean age 69.55 ± 0.85), we tested whether self-reported diabetes and hemoglobin HbA1c (HbA1c) levels were predicted by diabetes polygenic risk, cognitive ability measured about 60 years earlier, and their interaction...

Cognitive Ability Influences Reproductive Life History Variation in the Wild

Cognition has been studied intensively for several decades, but the evolutionary processes that shape individual variation in cognitive traits remain elusive [1-3]. For instance, the strength of selection on a cognitive trait has never been estimated in a natural population, and the possibility that positive links with life history variation [1-5] are mitigated by costs [6] or confounded by eco...

Linguistic Ability in Early Life and Cognitive Function and Alzheimer's Disease in Late Life

Design.Two measures of linguistic ability in early life, idea density and grammatical complexity, were derived from autobiographies written at a mean age of 22 years. Approximately 58 years later, the women who wrote these autobiographies participated in an assessment of cognitive function, and those who subsequently died were evaluated neuropathologically. Setting.-Convents in the United State...

Cognitive ability in childhood and cognitive decline in mid-life: longitudinal birth cohort study.

OBJECTIVE To examine the association between cognitive ability in childhood and mid-life cognitive decline in the normal population. DESIGN Longitudinal, population based, birth cohort study. PARTICIPANTS 2058 men and women born in 1946. MAIN STUDY MEASURES Ability in childhood measured by AH4 and test of verbal comprehension at age 15 years. Ability in adulthood measured by the national ...